Hey there! I hope you're doing good. I'm glad to see that you're so thoughtful for your friend. I feel sorry for the wife. She's going through a lot of pain already. She must be feeling helpless. I'd advice her to go for an IVF treatment. IVF works best with women having PCOS. This is because, in PCOS, your eggs aren't fertilized or have problems in doing so. While in IVF, the process is all about fertilizing the egg and sperm outside the body and then transferring the embryo into the uterus. This sure is a painful process. But once the surgery is done, it feels like a natural pregnancy. The end result is worth all the hassle, trust me. There are a lot of fertility clinics throughout the world. Choose the one with high success rates and affordable to them. Good luck!