Hey, Liza, I hope you and your sister are well. I am really sorry to hear about your sister's infertility. I can totally understand what she might be going through. I am on the same boat as hers. Every suggestion by a doctor is a big confusion in itself. Firstly she should make sure that the clinic she is visiting has a high success rate. I have realized the importance of good clinic after visiting one. It wouldn't be an exaggeration if I said it completely changed my life. Anyways, secondly, I think she should opt for IVF. It has been successful for so many couples I know. You just need to be patient and ready for the unexpected. It is unpredictable, so you never know if it will work for you or not in the first attempt. Other than that throughout the process stay calm. I am sure it will be a success for her. All my warm wishes are with her.